Isa is the name of Prophet Jesus (PBUH). Muslims believe Jesus was a Prophet without a father and the son of Mary the virgin (RA).
Almost as Adam had been created without a father or mother, Jesus Christ was born without a father. He was Allah's Word inspired to Mary. Allah gave him Clear Signs and endowed him with the Holy Spirit. He was held in honour both in this world and the Hereafter and in the company of those nearest to Allah. Jesus was strong in spirit, and very wise. Allah bestowed upon him the power to speak eloquently while still an infant in his cradle. Indeed, Jesus's miracles were innumerable. Allah taught him the Wisdom and Book, the Torah and the Gospel. Allah made him His Messenger to the Children of Israel. By Allah's leave, Jesus made the figure of a bird out of clay and breathed into it and it became a bird. He could, by Allah's leave, heal those born blind, lepers and even resurrect the dead. Jesus invited his people to worship Allah, the Only True God and obey Him as He should be obeyed; but they rejected him and rebelled. Only the poor among them followed him. Allah raised Jesus up unto Himself and saved him from those who plotted to crucify him.